Block-copolymerization by Metalic Sodium

Block and Graft Copolymerization by Controlled/Living Radical Polymerization Methods

Living polymerization and block copolymerization of alpha-olefins by an amine bis(phenolate) titanium catalyst.

An amine bis(phenolate) dibenzyl titanium complex having a methoxy donor on a side arm leads, upon activation with tris(pentafluorophenyl)borane, to unique living properties in alpha-olefin polymerization: exceptionally high molecular weight poly(1-hexene) is obtained in a living fashion at room temperature, living polymerization of 1-hexene is obtained above room temperature, and block copolym...

Surrounding tissue reaction of porous metalic implants

The development of advanced technology allows for more and more accurate analysis of the human body through the study of its biological processes. With the use of precise instruments of measurement we can model and project any bodily elements of interest. The immediate result of this is an increasing number of cases of use of various new materials in medical sciences. It is clear that these mat...

Mechanisms of atrial-selective block of sodium channel by ranolazine

1 Mechanisms of atrial-selective block of sodium channel by ranolazine 2 I. Experimental analysis of the use-dependent block 3 4 Andrew C. Zygmunt,* Vladislav V. Nesterenko,* Sridharan Rajamani, Dan Hu, Hector 5 Barajas-Martinez, 1 Luiz Belardinelli, 2 Charles Antzelevitch 6 7 Masonic Medical Research Laboratory, Utica, NY and 2 Gilead Sciences, Inc., Palo Alto, CA 8 *V.V.N. and A.C.Z. contribu...

Use-Dependent Block of Human Cardiac Sodium Channels by GS967.

GS-458967, 6-(4-(Trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (GS967) is a recently described, novel, sodium channel inhibitor exhibiting potent antiarrhythmic effects in various in vitro and in vivo models. The antiarrhythmic mechanism has been attributed to preferential suppression of late sodium current. However, there has been no reported systematic investigat...